Substances
About Database
Substances
About Database
Nervonic acid is a very-long-chain monounsaturated fatty acid (omega-9) and an organic carboxylic acid. It participates in myelin synthesis and regeneration, is a component of sphingolipids in cerebral white matter, and can be endogenously synthesized in the human body. Nervonic acid has significant dietary relevance, with effects comparable to those of arachidonic and eicosapentaenoic acids.
In clinical practice, nervonic acid is used in the management of demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, conditions in which reduced levels of nervonic acid are observed in brain sphingolipids. By supporting myelin integrity and remyelination processes, nervonic acid contributes to the maintenance of neural function. Dietary sources of nervonic acid include plant-based products such as flaxseed, sesame seeds, and yellow mustard seeds. These sources are recommended as nutraceutical support for the prevention of benign cognitive decline. Through its role in neural resilience and maintenance of white matter structure, nervonic acid may be classified as a proresilient substance rather than a cellular chronoblocker.
