Substances
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Glycine is the simplest aliphatic amino acid and a constituent of numerous proteins and peptides. It functions as an inhibitory neurotransmitter in the central nervous system, crosses the blood–brain barrier, accumulates in brain tissue, and exerts specific effects, including mild sedation. It may be used as part of combination therapy in patients with schizophrenia
Glycine is included in various pharmaceutical formulations used in neurology and psychiatry. It exhibits mild sedative and anticonvulsant effects and may improve mood, thereby enhancing patient adaptability in the presence of neurological or psychiatric disorders. These properties allow glycine to be classified as a proresilient substance (Janjira Soh et al., 2024). In addition, glycine-based solutions are used in urology for irrigation of the urinary tract during transurethral procedures. Glycine has also been described in sports medicine as a supportive agent during physical training, where it may contribute to accelerated muscle mass gain through the activation of creatine biosynthesis.